For some tasks it is desired to mount a microfluidic device on a surface and remove it afterwards for further operations. This might be the case, if an array on a glass surface should be further processed or if specimens should be removed from the microfluidic device. microfluidic ChipShop’s self-sealing and releasable chips address this task: With a soft component being part of the microfluidic device a liquid tight sealing on planar and clean surfaces can be achieved by a certain pressure. Removal of the microfluidic chip from the glass device can be done easily after completion of the fluidic operation. Next to the microfluidic chip a respective handling frame is at hand.