The SBS titer-plate format (85.48 mm x 127.76 mm) is a worldwide standard used by almost all pieces of equipment in the laboratory. A family of microfluidic microtiter plates having the spacing of the fluidic access holes of the laboratory standard and being compatible with the respective readers allows for a wide variety of different assays, including cell-based assays, hybridization assays, or small volume chemical synthesis. The plates are available in various polymer materials like PC, PS, PMMA, or COP (Zeonor), either in its native state or hydrophilically primed for self-filling of the microchannels with aqueous solutions. It is possible to include surface functionalization in the channels like the spotting of DNA probes, poly-L-lysin or collagen coating, etc. To easily integrate a microfluidic development into existing lab environments, we have developed a microfluidic platform with the outer dimensions of a standard microtiter plate.

The plate is equipped with four labeled sets of 16 microchannels each, with the dimensions 2 mm width, 150 μm height, and 18 mm length. Fluidic access is easily provided by conical openings of 2.5 mm diameter at either channel end.

These microfluidic microtiter plate devices are designed to have the fluidic access holes at the positions of a 384 well plate, having a 4.5 mm spacing. Read out positions comply with the positions of 96 well plate readers. The plates are available in two different channel depths.