Description
The scaffold and 3D culture integration chip Fluidic 1380 has 5 replicate functional units per chip and comes with Mini Luer interfaces. Each unit features a central compartment for sample integration, along with multiple inlet and outlet channels. This central compartment not only accommodates the incorporation of a scaffold (supplied by the customer) but also allows for the integration of complex structures like hydrogels and tissues. The inlet channels facilitate processes such as cell seeding, subsequent perfusion, and the introduction of various drugs into the sample.
The chip is designed as an open platform, allowing straightforward access to the central compartment for convenient sample integration. Additionally, each chip includes a pressure-sensitive adhesive tape that ensures easy sealing by the customer. Once the experiment is complete, the tape can be peeled off, enabling the retrieval of the sample for further downstream processing.
Scaffold-based 3D culture integration in microfluidic chips provides a versatile platform for creating physiologically relevant in vitro models of tissues and organs. This technology allows to closely mimic the natural microenvironment of cells, enabling better insights into tissue biology, disease mechanisms, and drug responses.