The chamber interaction chip Fluidic 688 possesses two cell culture chambers, which can be filled individually with different cell types. When used with different organ-specific cell types, the chip provides the possibility to mimic the exchange between these cells (e.g. kindey and liver) and enables to study interdependent cellular responses between organs and demonstrate that such tandem system can greatly improve the reproducibility and efficiency of e.g. toxicity studies. For more information, please refer to Theobald et al. (DOI: 10.1021/acsbiomaterials.7b00417).
Please note, if working with adherent cells, we recommend the use of hydrophilized chips as this will help your cells to adhere to the surface of the chip.